Meet LSA, The Psychedelic Found In Ancient Flowers

Explore the effects of this naturally-occuring psychedelic.

Evan Lewis-Healey
3 min readJun 9, 2021
.Seeds of this morning glory plant contain the psychoactive substance LSA. Photo taken by Heike Loechel on Wikimedia Commons

Psychedelic substances have the potential to shift perceptions and radically alter states of consciousness. While modern research is quickly becoming reacquainted with substances such as psilocybin and LSD, nature still yields many psychoactive compounds that are left understudied. One such substance yet to be placed under the microscope is LSA.

What is LSA?

LSA, or D-lysergic acid amide, is a psychedelic substance that’s structurally similar to LSD (lysergic acid diethylamide). However, unlike LSD, it does not need to be synthesized, as it occurs naturally. LSA is found in the seeds of morning glory, a group of more than 1,000 species of flowering plants.

One particular species of morning glory, Ipomoea corymbosa, is a climbing vine native to much of Central and South America. The seeds are referred to as Ololiúqui in the Nahuatl language, and were consumed by both the Mayans and Aztecs to induce trance states during ceremonies. LSA is also found in much higher concentrations in Hawaiian baby woodrose, another climbing vine native to India.

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Evan Lewis-Healey

PhD candidate at Cambridge University. Studying the cognitive neuroscience of altered states of consciousness.